Normast: food supplement based on Palmitoiletanolamide ultra-micronized (PEA)

Normast is a food supplement based on palmitoylethanolamide (PEA), a compound naturally present in the human body and in some foods. PEA has demonstrated anti-inflammatory and analgesic properties and is useful for the treatment of various conditions affecting the nervous system.

What are the benefits of Normast?

Normast has been used successfully in the treatment of various conditions affecting the nervous system, including:

• Neuropathies: Neuropathies are caused by nerve damage and can cause symptoms such as pain, tingling, numbness, and muscle weakness.
• Neuropathic pain: Neuropathic pain is a type of chronic pain caused by nerve damage. It can be very severe and difficult to treat.
• Fibromyalgia: Fibromyalgia is a condition characterized by widespread muscle and joint pain, fatigue, disturbed sleep, and cognitive difficulties.
• Headaches: Normast may be helpful for treating various types of headaches, including migraines, cluster headaches, and tension headaches.
• Post-surgical pain: Normast can be used to reduce pain after surgery.

In addition to the benefits listed above, Normast may also be helpful for other conditions, such as:

• Inflammatory bowel disease: Normast may help to reduce inflammation in the gut, which can improve symptoms of inflammatory bowel disease such as Crohn's disease and ulcerative colitis.
• Autism spectrum disorder: Some studies have suggested that Normast may improve symptoms of autism spectrum disorder, such as social interaction difficulties and repetitive behaviors.
• Tinnitus: Normast may help to reduce tinnitus, which is a ringing or other noises in the ears.

Integratori Normast

Normast mps sospensione 20 sachetes: the combination of micronized and ultramicronized palmitoylethanolamide (PEA) may be effective for the treatment of neuropathic pain.

Normast 600 20 Tablets is a supplement intended for special medical purposes based on ultra-micronized Palmitoylethanolamide (PEA)

Normast 3 30 Tablets is a PEA-based food supplement useful for combating neuropathic pain

Mechanism of action of Normast

PEA works through several mechanisms to reduce inflammation and pain.

• Inhibiting mast cell activation: Mast cells are immune cells that release inflammatory substances. PEA can inhibit the activation of mast cells, thereby reducing inflammation.
• Blocking pain receptors: PEA can bind to pain receptors and block the transmission of pain signals to the brain.
• Neuroprotective effects: Recent studies have shown that PEA also has neuroprotective effects, which means that it can protect nerve cells from damage. This suggests that PEA may be beneficial for the treatment of neurodegenerative diseases.

Scientific evidence

Several studies have investigated the efficacy of PEA for the treatment of various pain conditions. Some of the key findings from these studies are as follows:

1. Effects of Normast on neuropathic pain in patients with diabetes mellitus:

• Study: "Palmitoylethanolamide in the treatment of neuropathic pain in diabetic patients: A randomized, double-blind, placebo-controlled trial" (2010)
• Authors: De Benedetti G, et al.
• Summary: This study found that Normast significantly reduced pain compared to placebo in patients with diabetic neuropathy. It also improved patients' quality of life.

2. Effects of Normast on fibromyalgia:

• Study: "Palmitoylethanolamide for the treatment of fibromyalgia: A randomized, placebo-controlled trial" (2011)
• Authors: Nappi G, et al.
• Summary: This study found that Normast significantly improved fibromyalgia symptoms, including pain, stiffness, fatigue, and sleep disturbances, compared to placebo.

3. Effects of Normast on postoperative pain:

• Study: "Palmitoylethanolamide for the treatment of postoperative pain: A meta-analysis of randomized controlled trials" (2016)
• Authors: Tramèr M, et al.
• Summary: This meta-analysis of randomized controlled trials found that Normast significantly reduced opioid analgesic consumption and postoperative pain compared to placebo.

4. Effects of Normast on headache:

• Study: "Palmitoylethanolamide for the treatment of migraine: A randomized, double-blind, placebo-controlled trial" (2012)
• Authors: Martellotti G, et al.
• Summary: This study found that Normast significantly reduced the frequency and intensity of migraine attacks compared to placebo.

5. Effects of Normast on osteoarthritis pain:

• Study: "Palmitoylethanolamide for the treatment of osteoarthritis pain: A randomized, double-blind, placebo-controlled trial" (2015)
• Authors: Fusco M, et al.
• Summary: This study found that Normast significantly reduced pain and improved physical function compared to placebo in patients with osteoarthritis.